On Oct.9, Yi Zhong’s group published ’Social Isolation Induces Rac1-Dependent Forgetting of Social Memory’ in Cell Reports.
On August 8, 2018, a research team led by Professor Yi Zhong from School of Life Sciences and IDG/McGovern Brain Institute at Tsinghua University published a research article entitled Fan-Shaped Body Neurons in the Drosophila Brain Regulate Both Innate and Conditioned Nociceptive Avoidance in Cell Reports, reporting an important role of Drosophila Fan-shaped Body (FB) neurons in nociceptive avoidance.
On May 24, 2018, a research team led by Professor Kexin Yuan from the School of Medicine at Tsinghua University published a research article entitled A Distinct Anatomical Connectivity Patterns Differentiate Subdivisions of the Nonlemniscal Auditory Thalamus in Mice in Cerebal Cortext.
On Apr. 17, 2018, Xiaodong Liu‘s group published ’Improved calcium sensor GCaMP-X overcomes the calcium channel perturbations induced by the calmodulin in GCaMP’ in Nature Communications.
On Mar.22, 2018, Xiaodong Liu’s group published ’Cryo-EM structure of the polycystic kidney disease-like channel PKD2L1’ in Nature Communicaitons.
On March 15, 2018, a research team led by Professor Yi Zhong from the School of Life Sciences and IDG/McGovern Institute at Tsinghua University published a research article entitled Active Protection: Learning-Activated Raf/MAPK Activity Protects Labile Memory from Rac1-Independent Forgetting in Neuron. In this paper, the authors found that learning/training itself activates Raf/MAPK pathway to protect the newly formed labile memory from non-associative disruption. In other words, if such active protection mechanism is activated physiologically or by drug feeding, the English words you just remembered will not be forgotten because of a sudden phone call or a fire.
On Feb. 26, 2018, a research team led by Professor Minmin Luo from the School of Life Sciences and IDG/McGovern Institute at Tsinghua University published a research article entitled A hybridization chain-reaction-based method for amplifying immunosignals in Nature Methods.
On February 5th, 2018, the Yao lab’s new paper, entitled ‘CRISPR interference-based specific and efficient gene inactivation in the brain’, was published online in Nature Neuroscience. In this paper, Dr. Yao and colleagues reported their latest progress in establishing a dCas9/CRISPR-based gene silencing platform to achieve highly specific multiplex and conditional gene knockdown in the mammalian brain.