EN 中文

 

Chen, Runsen

Date：2019-09-30

PI, IDG/McGovern Institute, Tsinghua University

Associate Professor, Vanke School of Public Health, Tsinghua University

Office: 325, Jinchunyuan Building, Tsinghua University, Beijing, 10084

Email: runsenchen@tsinghua.edu.cn

 

             

 

                             

[Research Focus]

Our lab focuses on the mechanisms, risk identification, and intervention of mood disorders, self-harm, and suicidal behaviors. We investigate genetic vulnerability, interoceptive dysfunction, brain–body interactions, and related neural circuits. Using smartphones, wearable devices, and electrophysiological technologies, we develop multimodal digital phenotypes encompassing language, interoceptive measures, and multi-organ physiological signals, and identify digital biomarkers for dynamic risk monitoring. We also develop interoception-informed interventions for community and clinical populations, including transdiagnostic prevention, neuromodulation, and integrated psychosomatic care.

 

[Education & Experience]                           

2026-present  PI,   Tsinghua-IDG/McGovern Institute for Brain Research, Tsinghua University
2025-present          Deputy Director (Acting), Center for Psychological Development, Tsinghua University
2024-present          Associate Professor, Vanke School of Public Health, Tsinghua University
2021-2024              Assistant Professor, Vanke School of Public Health, Tsinghua University
2020                  DPhil in Psychiatry, University of Oxford
2017             Master’s degree, Brain and Mind Centre, University of Sydney
2015               Bachelor’s degree, School of Psychology, University of Sydney

 

[Selected Publications]                           

  • Qu, D., Zhang, X., Chen, D., Cai, T., Lin, J., Wang, S., Liu, J., Wen, X., Lei, C., An, J., & Chen, R.* (in press). Effect of an interoception-based universal prevention on non-suicidal self-injury among school adolescents. Nature Human Behaviour.
  • Liu, B., Wu, Z., Xue, M., Guo, J., Liu, S., Tong, Y., An, J., & Chen, R.* (2026). Interoception in self-harm and suicide: a scoping review and meta-analysis. Nature Human Behaviour.
  • Qu, D., Liu, B., Zhang, X., Cai, C., Chen, D., Liu, D., Wen, X., Wu, Z., Sun, S., Saxena, S., An, J*., & Chen, R.* (2026). School based suicide prevention using the gatekeeper programme: a cluster-randomized trial. Nature Health.
  • Lei, C., Geng, X., Wu, Z., He, X., Liu, K., Qu, D*., Xi, Y., An, J*., & Chen, R*. (2026). Digital mood phenotyping predicts short- and long-term suicidal ideation across a two-year timescale. Molecular Psychiatry.
  • Lei, C., Cui, Z., Duan, Y., Wu, Z., Qu, D., Wu, W., Zhang, C*., & Chen, R*. (2026). Integrating speech biomarkers and large language models for adolescent suicide risk detection with mobile application for real-world evaluation. Cell Reports Medicine.
  • Luo, X., Zhang, Q., Qu, D., Zu, Y., Wang, S., Jin, Y., Liu, B., Xu, Y., Li, N., Tian, X., Huang, X., Shirazi, A., Zheng, R*., & Chen, R*. (2026). Universal school-based transdiagnostic interventions to improve mental health and well-being among Chinese adolescents: A cluster randomised controlled trial. Lancet Child & Adolescent Health.
  • Wen, X., Sun, S., Lin, D., Yue, W*., & Chen, R*. (2025). A social-ecological approach on social contagion of self-harm. Nature Reviews Psychology.
  • Wen, X., Sun, Y., Wang, S., Yue, W*., & Chen, R*. (2025). Genetic and neurobiological mechanisms underlying transition in self-injury thoughts and behaviors during adolescence. British Journal of Psychiatry.
  • Sun, Y., Liao, Y., Zhang, Y., Bi, W., Chen, R*., & Yue, W.* (2025). Multitrait GWAS of non-suicidal self-injury and the polygenetic effects on child psychopathology and brain structures. Cell Reports Medicine.
  • Wen, X., Qu, D., Liu, D., Shu, Y., Zhao, S., Wu, G., Cui, Z*., Zhang, X*., & Chen, R.* (2024). Brain structural and functional signatures of multi-generational family history of suicidal behaviors in preadolescent children. Molecular Psychiatry.
  • Wen, X., Qu, D., Wang, Y., Cui, Z*., Zhang, X*., & Chen, R.* (2023). The transition trajectories of self-injurious thoughts and behaviors among children from biopsychosocial perspective: a population-based cohort study. Nature Mental Health.
  • Chen, R#., Cui, Z#., Capitao, L., Wang, G., Satterthwaite, T. D., & Harmer, C. J. (2020). Precision biomarkers for mood disorders based on brain imaging. BMJ.