| Time | 12:00-13:00, Oct 25, 2022 |
| Venue | E203, Biomedicine Hall, Tsinghua University |
| Host | |
| Speaker | Chi Liu (刘驰) |
| Topic | Simultaneously optical recording and manipulating neural activities across layers and regions in neuron system in vivo |
| Abstract | The integration and coordination of multiple brain regions are significant mechanisms of information processing. We propose across-plane all-optical physiology, to simultaneously record and manipulate neural activities at different depths spanning from 0 μm to 620 μm, based on two-photon fluorescence imaging and two-photon optogenetics. We demonstrate the application of across-plane all-optical physiology in deciphering neural circuits in cortical columns and in hippocampus layers in vivo. Across-plane all-optical physiology opens the window of all-optical interrogation of neural circuits across brain regions, promising for the study of long-range functional connectivity. |
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