Time: 14:00-15:30 on Tue.,Nov.28, 2023

Venue：E109,Biomedicine Hall

Speaker: Dr.Zhenge Luo

Host: Dr.Da Mi（米达）

Title: Molecular mechanisms linking the evolution of human brain and neuronal cytoarchitecture

Abstract：

The expansion of the cerebral cortex and the increase in neuronal complexity during hominoid evolution are assumed to be associated with the acquisition of higher intelligence in human species. These features are determined by amplification of specific types of neural progenitors and prolonged patterns of neurogenesis and maturation. While the processes of cortex development are generally conserved among mammals, they have evolved in primates, particularly in humans, through the emergence of species-specific novel genes and/or cell type-specific transcriptional elements. This lecture will introduce the evo-devo studies on human cortex development, highlighting genetic, molecular, and cellular basis of human brain evolution.

Biography：

Dr. Zhen-Ge Luo, Professor, Executive Dean, School of Life Science and Technology, ShanghaiTech University.Dr. Luo graduated from Nankai University in Tianjin, China in 1988. He obtained Ph.D from Chinese Academy of Military Medical Sciences and accepted postdoctoral training in the Department of Neurobiology, University of Alabama at Birmingham (UAB), the United States of America. In 2003, he joined the Institute of Neuroscience (ION), Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), as a Principal Investigator. In 2018, he joined School of Life Science and Technology, ShanghaiTech University, as a tenured full professor. His research concentrates on neural development, degeneration, and regeneration, including cortex development and evolution, neuronal growth and repair, aging related neuronal disorders. Currently, Dr. Luo serves as a vice president for the Chinese Society for Cell Biology, an executive council member of the Chinese Neuroscience Society chairing the Neurodevelopment and Regeneration Branch.