Jia, Xiaoxuan

 PI, IDG/McGovern Institute for Brain Research, Tsinghua University
 PI, Center for Life Science
 Associate Professor, School of Life Science, Tsinghua University


 Lab website: https://jiaxx.github.io/


[Research Focus]

We seek to understand the neural computations underlying flexible perception and cognition. Our research lies at the intersection of systems, computational, and cognitive neuroscience. In particular, we are interested in understanding how visual sensory information is represented and propagated in the mammalian brain. Our approach combines large-scale in vivo electrophysiology, closed-loop brain-machine interface (BMI), machine learning, neural network modeling and quantitative (online) human psychophysics.


[Education & Experience]

2022-present   Principal Investigator, IDG/McGovern Institute for Brain Research at Tsinghua University/ Center for Life Sciences, Beijing, China.

2022-present   Associate Professor, School of Life Sciences, Tsinghua University, Beijing, China.

2016-2022        Senior Scientist and Principle Investigator, Allen Institute, US.                     

2012-2015        Postdoc, Department of Brain and Cognitive Sciences/McGovern Institute for Brain Research, MIT, US.    

2006-2012        Ph.D., Department of Neuroscience, Albert Einstein College of Medicine, US.                    

2005-2006        Visiting Student, Department of Systems and Computational Biology, MIT, US.               

2001-2005        B.S. Department of biological sciences and biotechnology, Tsinghua University, China.  

[Selected publications]
  • Jia X*, Siegle JH, Durand S, Heller G, Ramirez T, Koch C , Olsen SR. (2022) Multi-regional module-based signal transmission in mouse visual cortex. Neuron doi: https://doi.org/10.1016/j.neuron.2022.01.027
  • Jia X*, Hong H, DiCarlo JJ. (2021) Unsupervised changes in core object recognition behavioral performance are accurately predicted by unsupervised neural plasticity in inferior temporal cortex. eLife 2021;10:e60830 (Simons foundation global brain recommended)
  • Siegle JH*, Jia X*, Durand S, Gale S, Bennett C, Graddis N, Heller G, ... Olsen SR*, Koch C. (2021) A survey of spiking activity reveals a functional hierarchy of mouse corticothalamic visual areas. Nature 592, 86-92
  • Jia X*, Siegle JH, Bennett C, Gale SD, Denman DJ, Koch C, Olsen SR*. (2019) High-density extracellular probes reveal dendritic backpropagation and facilitate neuron classification. Journal of neurophysiology 121 (5), 1831-1847
  • Billeh YN, Cai B, Gratiy SL, Dai K, Iyer R, Gouwens RW, Abbasi-Asl R, Jia X, Siegle JH, Olsen SR, Koch C, Mihalas S, Arkhipov A*. (2019) Systematic Integration of Structural and Functional Data into Multi-Scale Models of Mouse Primary Visual Cortex. Neuron. NEURON-D-19-01027
  • Garrett ME, Manavi S, Roll K, Ollerenshaw DR, Groblewski PA, Kiggins J, Jia X, Casal L, Mace K, Williford A, Leon A, Mihalas S, Olsen SR*. (2020) Experience shapes activity dynamics and stimulus coding of VIP inhibitory and excitatory cells in visual cortex. eLife 2020;9:e50340
  • Jia X*, Xing D, Kohn A. (2013) No consistent relationship between gamma power and peak frequency in macaque primary visual cortex. Journal of Neuroscience 33 (1), 17-25
  • Jia X*, Tanabe S, Kohn A. (2013) Gamma and the coordination of spiking activity in early visual cortex. Neuron 77 (4), 762-774 (Faculty 1000 recommended)
  • Jia X*, Smith MA, Kohn A. (2011) Stimulus selectivity and spatial coherence of gamma components of the local field potential, Journal of Neuroscience 31 (25), 9390-9403
  • Smith MA, Jia X, Zandvakili A, Kohn A. (2012) Laminar dependence of neuronal correlation in macaque V1. Journal of Neurophysiology. DOI:10.1152/jn.00846.2012.
  • Jia X, Kohn A. (2011) Gamma rhythms in the brain. PLoS Biology. 9(4):e1001045.