研究员，清华-IDG/麦戈文脑科学研究院     教授、主任医师，清华大学附属北京清华长庚医院神经内科

[研究兴趣]   

本课题组长期致力于缺血缺氧性神经损伤类疾病的基础和临床研究，利用细胞生物学、分子生物学、免疫学、遗传学、行为学、神经分子影像学等研究手段，围绕神经组织和脑血管组织之间的信号传导、物质交换、损伤与修复等方面展开研究。采用干细胞衍生物结合生物材料等组织工程交叉技术为缺血缺氧性神经损伤提供新的治疗方法，同时探索将新材料和AI 技术应用于神经系统疾病诊疗的科研和临床工作，为新的诊疗方法和精准医疗奠定基础。

[简历]                             

[部分发表]                             

• Yan Zhao ,... Jian Wu* and Xianghua Fang*.Prevalence and Risk Factors Comparison of Anterior and Posterior Intracranial Arterial Stenosis.Evidence-Based Complementary and Alternative Medicine.Volume 2022, Article ID 7710374, 8 pages.
• Gao C, Jia W, ... Wu, J*. Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke[J]. Journal of neuroinflammation, 2021, 18(1): 1-16.
• Song, X., Wei, Q., Zhao, X., Hou, D., Zhao, H., Wang, L., ...  Wu, J*. (2021). Association between Short-Term Blood Pressure Variability and Intracranial Atherosclerotic Plaque Vulnerability: A High-Resolution Magnetic Resonance Imaging Study. Journal of atherosclerosis and thrombosis, 63164.
• Song X, ...  Wu, J*..  Association between blood pressure and intracranial artery stenosis in a Chinese population[J]. The Journal of Clinical Hypertension, 2020
• Song X , Zhao X , Liebeskind D S, ...  Wu, J*. Associations between systemic blood pressure parameters and intraplaque hemorrhage in symptomatic intracranial atherosclerosis: a high-resolution MRI-based study[J]. Hypertension Research, 2020, 43(7)
• Xu W , Gao C , ...Wu J. CD151 Alleviates Early Blood–Brain Barrier Dysfunction After Experimental Focal Brain Ischemia in Rats[J]. Cellular and Molecular Neurobiology, 2020:1-12.
• Song X , Zhao X , Liebeskind D S, ...  Wu, J*. Incremental value of plaque enhancement in predicting stroke recurrence in symptomatic intracranial atherosclerosis[J]. Neuroradiology, 2020.
• Song X, Xue S, Wu J*. Isolated symptomatic middle cerebral artery stenosis in young adults: clinical prognosis and vascular change[J]. Int J Neurosci, 2017,127(7):573-578.
• Song X, Xue S, Zhao J, , ...  Wu, J*. Screening for Fabry's disease in young patients with ischemic stroke in a Chinese population[J]. Int J Neurosci, 2017,127(4):350-355.